The main conservative therapy uses thyrostatics, medicines that block the synthesis of thyroid-stimulating hormones. The most popular drugs in this class are imidazole and thiouracil. In most cases, a correctly selected dosage of these will bring about a rapid regression of symptoms. A further advantage of thyrostatics is their ability to reduce immune cell activity.
Once the pathological symptoms have been halted and hormone levels normalized, the dosage of thyrostatics is reduced. Treatment is carried out under close medical supervision. These drugs are prescribed for long periods, up to 18 months. There is a recurrence within a year of stopping thyrostatics in about a half of cases.